Tell your doctor about the allergy and what signs you had. Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. Venofer (iron sucrose): Basics, Side Effects & Reviews - GoodRx They can give you tips on how to deal with any side effects that may be bothersome. Injectafer contains the active drug ferric carboxymaltose, while Feraheme contains the active drug ferumoxytol. Injectafer isnt known to interact with any other medications, herbs, supplements, or foods. On the other hand, some people may have a poor appetite that goes away when their anemia is treated. But in some people, Injectafer can cause symptoms of hypophosphatemia to occur. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. In one study, people were given either Injectafer or an iron replacement drug called Venofer. reactions at the site of the injection. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. This site is intended for use only by US patients. If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. But its only approved for use in people with CKD who may or may not need dialysis. It depends. Hypophosphatemia risk appears to be substantially lower with other IV iron formulations. * This is a partial list of mild side effects from Injectafer. If you have questions about drinking alcohol while youre taking Injectafer, talk with your doctor. So you wont pick up this medication from a pharmacy. During Injectafer treatment, your doctor will likely order blood tests. If you have more questions about how Injectafer will affect your anemia, talk with your doctor. Otherwise, call a poison control center right away. For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). You should not receive Venofer if you have known allergies to iron sucrose. Dilute Venofer in a maximum of 250 mL of 0.9% NaCl. But keep in mind that in this study, delayed allergic reaction only occurred in one person. Brandon ColbyMD, a medical expert specializing in preventive medicine and clinicalgenomics. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. These lists dont include all possible side effects. Weight influences how fast medication breaks down in the body, so it also affects how longside effectswill last. Call your doctor right away if youre having a severe allergic reaction to Injectafer, even if youve had doses of the drug in the past without any problems. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. With IV infusion, the drug is given as a slow drip into your vein over a period of time. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? Iron is important for many functions in the body, especially for the transport of oxygen in the blood. Constipation,dry mouth, headaches, upset stomach, and many othercommonside effectscan greatly affect peoples quality of life, though. Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. Generics tend to cost less than brand-name drugs. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Do not exceed 1,500 mg of iron per dosing course. All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. I can't take oral supplements because they cause horrible debilitating Constipation. As with most drugs, some people can have an allergic reaction after taking Injectafer. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Discuss the risks and benefits with your doctor. In one study, treatment with Injectafer was compared with that of iron thats taken by mouth. endobj Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. How is Venofer (iron sucrose) given? There are different types of anemia, but IDA is the most common type. Dizziness. If that happens, and your doctor thinks Injectafer is a good treatment option for you, you can receive another treatment course of the drug. stream Depending on your anemia symptoms, your weight changes may be different than those described here. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Common and Rare Side Effects for Venofer Vial - WebMD The information provided is not intended to replace your healthcare provider's medical advice. Hypophosphatemia seems to mostly occur in people who are already at risk for low phosphorus levels. Common Venofer side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting, diarrhea; muscle or joint pain, back pain; pain or swelling in an arm or leg; itching; or bruising or irritation where the medicine was injected. Amounts of iron ingested by the infant would be normal and are not expected to cause any adverse effects in breastfed infants. 3 0 obj Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. The following information describes dosages that are commonly used or recommended. Then your body uses that iron to make hemoglobin and RBCs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. To help make sure that you dont miss appointments for your Injectafer doses, try setting an appointment reminder on your phone. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). * Sex and gender exist on spectrums. }|54U|O~?|_v;f\o^(W+/-|^)O65_)rd sm }[x[)y.z Wz?9_jV0ub,`g`s?oXOSp/Kgw$b!Vb$;IvBVR9n|\0ln=;/=,mgw@do,[";/8nJL{n}Bb-|^6[~>a_1H'^M:^vv=iM+x|+Y Many patients with kidney disease cannot get enough iron from food and require injections. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. You may also report side effects at https://www.fda.gov/medwatch. Data on file, American Regent, Inc. 1. Learn more about these, as well as the symptoms, diagnosis, and treatments. And the drug has also been studied in children with IDA who have inflammatory bowel disease (IBD). (One treatment course includes two doses of the drug.) People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. Symptoms include shock, dangerously low blood pressure, loss of consciousness, and/or collapse. Once inside your body, ferric carboxymaltose releases iron into your system. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. Last updated on Feb 20, 2023. Can poor sleep impact your weight loss goals? However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. muscle pain. Cholesterolmedication may reduce the risk of a stroke but it can decrease the quality of life for some people but causingweight gain, dizziness, nausea, and musclepain. Why is the range so wide? Iron infusion: Uses, benefits, and what to expect - Medical News Today A lack of iron can lead to iron deficiency anaemia if left untreated. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. If needed, theyll recommend treatment, including certain medications. If you notice other effects not listed above, contact your doctor or pharmacist. Fortunately, knowing how longside effectslast can help those suffering know what to donext. Call your doctor right away if you have serious side effects. The study also didnt show if one treatment was worse than the other. Cancer patients who have anemia and are taking an ESA. These side effects can range from being mild to severe. VenAccess is a trademark of Vifor (International) Inc. Switzerland. There isnt a known interaction between Injectafer and alcohol. A healthcare provider will give you this injection. Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. Intravenous Iron Infusion - Cleveland Clinic Hemoglobin is a protein thats found inside your red blood cells. Notify your healthcare provider of any irritation at the injection site. This may lead to the person needing a higher dose compared to someone who is muchsmaller. Injectafer can cause mild or serious side effects. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). Injectafer (ferric carboxymaltose): Side effects and more Source: Wolters Kluwer Health. Selected from data included with permission and copyrighted by First Databank, Inc. Its given by either intravenous (IV) infusion or slow IV injection. Red Tide in Florida: What You Need to Know | OutCoast.com Venofer pregnancy and breastfeeding warnings. Heart failure: Could a low sodium diet sometimes do more harm than good? Below are examples of these side effects. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. For more information about Injectafers approved uses, see the section Injectafer uses below. Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. Upset stomach or throwing up. Serious side effects from Injectafer arent common, but they can occur. You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. But for other people, their anemia may come back after Injectafer treatment. To make sure Venofer injection is safe for you, tell your doctor if you have: hemochromatosis or iron overload (the buildup of excess iron). It is usually given slowly over 2 to 5 minutes or as directed by your doctor. You will be watched closely by your doctor for 30 minutes after each dose. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. What to Know About Iron Infusions for Anemia Treatment - GoodRx If you think there has been an overdose, call your poison control center or get medical care right away. Any long-term side effects/dangers from iron infusions? If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). You may wonder how Injectafer compares with other medications that are prescribed for similar uses. Not all possible drug interactions are listed here. fever. For information on Injectafers effectiveness in treating IDA, see the Injectafer Uses section below. Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. Consult the product instructions and your pharmacist for storage details. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. Venofer may cause significant hypotension (decreased blood pressure). If you are allergic to Venofer; any part of this medicine; or any other drugs, foods, or substances. Venofer | Uses, Dosage, Side Effects, FAQ - MedicinesFAQ Effectiveness of Injectafer compared with iron thats taken by mouth. Any long-term side effects/dangers from iron infusions? : r/Anemic - Reddit If you have questions about side effects, call your doctor. Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. The researchers found that compared with their hemoglobin level before the study: But the actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. 1xo`[kg'#KS#.#`uv:PM1+Ob`>y/8:6Ghl:y9B+-,9m[ The drug helps increase your hemoglobin level back to a value thats within the normal range. These lists contain examples of serious side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). 2022 American Regent, Inc.PP-VE-US-0016 (v6.0)1/2022, Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your organs and tissues through hemoglobin, If you or your child has been prescribed Venofer, its based on your blood work, which shows how many red blood cells you have and whether you have enough iron in your blood cells, If you are iron deficient, raising your iron levels can help increase your hemoglobin levels, Treating your anemia may help prevent future health problems, Over time, untreated IDA can cause heart problems; if you already have heart problems, it can make those problems worse, Venofer is given intravenously (through an IV) and Injectafer begins working as soon as it enters your body. In the study, peoples hemoglobin level was measured to check for improvement in their anemia. There are 2 tests that your doctor will likely Answer by DrLact: About Venofer usage in lactation. This is why the FDA hasa programcalledMedWatchthat encourages Americans to report adversereactions. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. Keep in mind that there may be additional costs related to getting your doses of the drug at a medical facility. But even if youre not at risk for the condition, your doctor may still monitor your phosphorus levels. You may report side effects to FDA at 1-800-FDA-1088. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. In clinical studies, people who took Injectafer still had iron in their system that was released by the drug 24 days after theyd gotten their injection. The factors influencing how longside effectslast may not provide the answer most are looking for, but it does explain why some people cant take certain medications because theside effectsareunbearable. Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; After getting each dose of Injectafer, your healthcare professional will monitor you for at least 30 minutes. Before you receive Venofer, tell your doctor if you have low blood pressure, hepatitis, or if you have received many blood transfusions in the past. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Someside effectsare temporary or last as long as the person continues takingprescription medicine. Call your doctor for medical advice about side effects. xmq92\Kz!yIP}2~(?c/JUCK2~o_N=>K$o/_7'Z+nRkKM^y{u|ZFh$v}]O~vfo=.GowGFodVj-[-~x]Kg~9H'%h={OX/#S|Mc~|]_2nv`wwotn/+$G[{hGrP}sbZG-RGf#l~~l|Qnccml_iPy]G\17c,yPF[28z&I'+B(?rrvi,G?}/;'?;pm>?.i42ONmk~ai_u0z9o_? A delayed reaction can occur in two different ways: It can happen hours or days after you receive a drug, or it can happen after a second (or later) dose of a drug. <> This gives a total cumulative dose of 1,500 mg of Injectafer. People who weigh 110 pounds (about 50 kilograms) or more will receive two separate Injectafer doses of 750 milligrams each. Venofer may cause serious side effects including: problems with your dialysis vein access point, chest pain, severe headache, blurred vision, pounding in your neck or ears, lightheadedness, pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, and fever Get medical help right away, if you have any of the symptoms listed above. I actually was constipated after my 3rd but didn't think anything of it. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. As a result, you may not make as much EPO as usual. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). I used to get a different type but my . These are not all the side effects that may occur; contact your healthcare provider if you have questions. Your doctor will do laboratory tests to monitor your response. It's a more immediate treatment than supplements or dietary changes. Brand-name medications usually cost more than generics. (A medication class is a group of medications that work in a similar way.). Injectafer and Venofer have different approved uses, but theyre both used to treat IDA in people with CKD. It is very important that your doctor check you closely while you are receiving this medicine. I hope you found answers and are feeling better now. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. Common side effects of Venofer include: muscle cramps, nausea, vomiting, stomach pain, strange taste in the mouth or decreased sense of taste, diarrhea, constipation, headache, cough, sore throat, sinus pain, congestion, back pain, joint pain, dizziness, weakness, tired feeling, anxiety, ear pain, swelling of the arms/legs, or This medication is given by injection into a vein as directed by your doctor. (And Injectafer is used to treat IDA.) wAd**CgI%"nn{Oa[q{r5 If you have questions about using Injectafer in a child, talk with your doctor. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. They can recommend appropriate treatment options. pain in the arms or legs. Knowing how longside effectslast can help with the decision on whether to use a particulardrug. Injectafer can cause low blood levels of phosphorus, which is a condition called hypophosphatemia. . The researchers looked to see how well each drug worked to increase peoples hemoglobin level.
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